Ginkgolide B (GB), a terpene lactone and active ingredient of Ginkgo biloba, shows protective effects in neuronal cells subjected to hypoxia.We investigated whether GB might protect neurons from hypoxic injury through regulation of neuronal Ca2+ homeostasis.Primary hippocampal neurons subjected to chemical hypoxia (0.7 mM CoCl2) in vitro exhibited
Notopterygium incisum C.C.Ting ex H.T.Chang (Apiaceae) is an endangered perennial herb in China.The lack of transcriptomic and genomic resources for N.incisum greatly hinders studies of its population genetics and conservation.In this study, we employed RNA-seq technology to characterize transcriptomes for the flowers, leaves, and stems of this end
Abstract Background In 2014, nursing home administration and government officials were facing increasing public and media scrutiny around the variation of antipsychotic medication (APM) prescribing across Ontario nursing homes.In response, policy makers partnered to test an academic detailing (AD) intervention to address appropriate prescribing of
Valproic acid holds a prominent position as the primary therapeutic option for epilepsy cases.The utilization of antiepileptic agents like valproic acid has been linked Bath Safety to disturbances in sleep architecture.Although scant, there exists a subset of studies that allude to the potential manifestation of sleep apnea as an adverse effect of